Guide
Borderlands 4 Endgame Guide
Endgame on Kairos is boss targets (Bloomreaper, Bio-Bulkhead), Order bunker chest loops, Maurice weekly legendaries, and high-tier Vaults spent with key fragments.
Lock a character build page (Vex/Rafa/Harlowe/Amon) and farm only that loot filter.
Rotate Bio-Bulkhead and Bloomreaper for Hot Slugger and Bulkhead Breaker.
Clear Dominion chests for Ripper and Hyperion legendaries.
Use DLC bounty packs for weekly variety if you own Super Deluxe.
Last verified Sep 26, 2026